Brandon King scored the highest for West Indies with an unbeaten 85 off 55 deliveries while Romario Shepherd scalps four.
India defeated the West Indies by nine wickets in the fourth match of the five T20 series on 12 August.
Earlier, Kuldeep Yadav and Axar Patel were the star performers as West Indies were kept to 159.
Nicholas Pooran, Akeal Hosein win battle of nerves to make it 2-0 for West Indies.
Holder and co stoutly defend 149 as West Indies beat India by 4-runs in 1st T20I.
Gill, Kishan, Samson and Hardik scored fifties to set up a tall chase, before the bowlers cleaned up West Indies for 151.